Clinical Chemistry

Cerebrospinal Fluid (CSF)

CSF is a clear liquid produced in the ventricles of the brain; fills and protects cavities in the brain and spinal cord. The fluid is stainless. When collecting, CSF, make sure that all necessary precaution is adhere to, to avoid contaminating the sample. CSF is often sent to clinical laboratory for analysis of protein, glucose […]

Clinical Chemistry

Faecal Specimens

Collection of faecal specimens can either be of early morning, timed, or random. The methods of collection depend on the types of investigation requested. When investigating for qualitative analysis, i.e. occult blood test is requested, then a number of random specimens should be collected for the investigation. Small, clean, dry, wide mouth and sterile Containers, […]

Clinical Chemistry

Preservation of urine

Chemical change often take place in urine when the are left standing at room temperature for a long period of time. Below are some of the change; Urea breakdown to ammonia via bacteria action, as such resulted in raising of urine pH. Urobilinogen is oxidized to urobilin when urine is left to stand at room […]

Clinical Chemistry

Urine Specimens

Urine is an essential specimen for clinical investigation. Single urine specimens may be enough for biochemical investigation base on the type of test requested. Just like other sample, containers for urine collections must be clean, dry, grease free, leak proof, should have sufficient wide mouth and free from any contamination, either chemical or biological for […]

Clinical Chemistry

Blood specimens

When collecting blood sample for biochemical analysis, the specimens containers used to collect the blood must be leak proof and biologically and chemically clean, needle and syringe also must be free of all contaminants, either biological or chemical, and must be sterile. The most acceptable method of collecting blood sample for biochemical analysis, is via […]

Clinical Chemistry

Pre-analytical Quality Control

Pre-analytical: these are quality control applied before the commencement of the analysis. These type of quality control include patients status and collection of blood. Patient status Patient Status: can simply be refer as the physiological condition of the patient at that point when collecting blood sample for diagnostic analysis. These are to reduce the differences […]

Clinical Chemistry

Deionization

Water Deionization Deionization is another way to obtain water that is chemically pure. The mechanism behind these, is that tap water is passed through anion and cation exchange resin, on the resin any ion present in the water will be exchange with hydrogen and hydroxide ion from the resin. The cation is made of hydrogen […]

Clinical Chemistry

WATER DEIONIZATION

WATER STILLS AND DEIONISERS In performing various laboratory tests, basically in clinical chemistry, pure water is the requirement for use. These pure form of water are sourced/gotten either by distillation or deionisation processes respectively. Distillation This is a process of subjecting water to high temperature resulting to the formation of steam which is then condensed […]