Lifestyle modification, e.g. weight optimisation, smoking cessation and regular sexual intercourse.
Investigation of semen analysis and prolactin level.
Mid-luteal (day 21) progesterone assay. > 30 nmol/L suggests adequate ovulation.
Laparoscopy and/or hysterosalpingography (Specialist supervision).
Treat the underlying disease.
For induction of ovulation:
- Clomifene, oral, 50 mg daily on days 5–9 of the cycle. Specialist only.
o Monitor the progress of ovulation.
For hyperprolactinaemia after further investigation: SEE Prolactinoma.