ACETYSALICYLIC ACID=ABC (ASPIRIN)

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Function: (Antipyretic, Analgesic, Non-steroidal Anti-inflammatory Drugs)

Antipyretic: a medicine that lowers or prevent raising of body temperature (fever).

Analgesic: medicine that help to relieves pains.

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Non-steroidal Anti-inflammatory Drugs(NSAID): as the name imply, it is a drugs that did not contain steroid, and work by preventing the activity of cyclooxygenase1 enzymes (an enzyme that regulates prostaglandins which are important for the health of the stomach lining and kidneys) and cyclooxygenase2 enzymes (an enzyme that makes prostaglandins which cause inflammation and pain and fever).

Usage

For treating the following ailment;

mild pain

Fever: frequent rising temperature of the body, which signify sign and symptom of infection.

Rheumatic diseases: is a painful disorder of the joints, muscles and any connective tissues in the body system. (excluding gout).

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Availability

100mg, 300mg and 500mg tablet

Prescription

Children above  20kg,  should be given 100mg/kg/day in 4 divided doses, and should not exceed 100mg/kg/day.

Adult 3 to 6g/day in 4 divided doses, and should not exceed 6g/day

Prescription Table

Age 0 to 2mth 2mth to 1yrs 1yrs to 5yrs 5yrs to 15yrs 15yrs to adult
Wight 0kg to 4kg 4kg to 8kg 8kg to 15kg 15kg to 35kg 35kg above
100mg tab Nil Nil 1 ½ tab x 3 3 tab x 3 Nil
300mg tab Nil Nil  ½ tab x 3 1 tab x 3 2 tab x 3
500mg tab Nil Nil  ¼  tab x 3 ½  tab x 3 1 tab x 3

Duration of administration for mild pain and fever, is 1 to 3 days but for rheumatic disease; is according to how the patient responds to clinical treatment.

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Precautions

Do not administer to the following patient;

  1. Patient who is allergic to aspirin, and NSAID.
  2. Coagulation disorder
  3. Hepatic or cardiac problems
  4. Severe renal problem
  5. Peptic ulcer
  6. Haemorrhage
  7. Children less than one years

Use paracetamol for children less than one years

Administration to elder and asthmatic patient is guided with a strict caution.

And never exceed the dosage limit mostly in children and elderly. Overdose led to intoxication which might probably be fatal.

Stop the medication and use paracetamol when the following sign and symptom occur;

  1. Early sign of overdose
  2. Dizziness
  3. Allergic reactions
  4. Peptic ulcer
  5. Epigastric pain
  6. Haemorrhage

Usage Advice

Never combine aspirin with antcoagulant, methotrexate and NSAID.

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When combine with insulin, proper monitoring of the patient should be adhere to because it may cause the following; increased hypoglycemia, and corticosteroids.

For pregnant and breast feeding patient, use paracetamol.

Take the drugs meals with plenty of water.

For moderate pain treatment, aspirin can be combine with codeine or tramadol.

It can also be administer for antipletet work in secondary prevention of atherothrombosis, in an average dose of 75 to 300mg daily.

Never use when the tablet has and excessive  smell of vinegar, but small quantity of vinegars is always present.

Always store at temperature 25ºC.

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